- A Case of Achieving Complete Remission with Stereotactic Body Radiation Therapy in Patients with Hepatocellular Carcinoma with Macrovascular Invasion after Repeated Transarerial Chemoembolization
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Sang Youn Hwang, Seon-Mi Lee, Jong Woo Im, Ki Jeong Jeon, Sang Bu Ahn, Eun Kyeong Ji, Jin-Young Park, Cheol-Won Choi Choi, Gwang-Mo Yang
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J Liver Cancer. 2016;16(2):123-128. Published online September 30, 2016
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DOI: https://doi.org/10.17998/jlc.16.2.123
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 Abstract
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- Transarterial chemoembolization (TACE) is the worldwide procedure performed for patients
with various stage hepatoceullar carcinoma (HCC), but is not yet considered as curative
treatment because of relatively high local recurrence rate. Moreover, many clinicians
frequently experience treatment failure (incomplete necrosis or stage progression etc.) after
repeated TACE, but no clear guidelines have been recommended about salvage treatment
modalities for this situation. Recently, studies for combination of radiation therapy and TACE
for HCC with TACE refractoriness have been tried and reported better therapeutic efficacy.
Based on above suggestions, we herein offer our experience of a patient with macrovascular
invasion developed after repeated TACE that achieve complete remission by stereotactic
body radiation therapy. Further study, maybe regarding a combination of locoregional and
systemic therapy, is necessary on how to manage HCC patients with TACE refractoriness.
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THE KOREAN LIVER CANCER ASSOCIATION
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